Single-A Lakeland outfielder Avisail Garcia went on the seven-day disabled list Wednesday due to a hamstring injury.
Detroit hasn't won consecutive games since April 18. Max Scherzer is back on the mound for the Tigers for the first time since striking out 15 Pirates.
Ramon Santiago will start at second base and bat ninth in place of Ryan Raburn, but the rest of the lineup is the same as it was Friday night in a 10-6 victory over the Twins.
Jim Leyand: "I don't want to put the cart before the horse. ... Let's just try to sustain it a little bit and then we'll talk more about it."
The Tigers finished the game 9-for-16 with runners in scoring position after going 3-for-28 in those situations in three games against Cleveland.
Detroit scored 10 runs on 16 hits to snap a three-game losing streak.
Balester: "I really enjoyed my time with the Tigers, and I like all the players, coaches and everyone in the front office. I just wish I would have pitched better."
The Tigers appear hopeful Jackson will be able to return from the disabled list as soon as he is eligible to, which is next Friday at home against the New York Yankees.
Raburn, who missed the three-game series against the Cleveland Indians while on bereavement leave, will bat ninth for the Tigers.
When Justin Verlander threw a 101.5 mph four-seamer with his second-to-last pitch Thursday, it was pretty apparent the nagging callus on his thumb wasn't a problem.
Leyland said Thursday that he's open to suggestions, with one exception. He has no intention of flip-flopping Miguel Cabrera and Prince Fielder in the lineup.
Justin Verlander has officially reached the point where it's no longer OK to excuse the Detroit Tigers' struggles based on it being too early in the season.