Michigan coach Rich Rodriguez said on his radio show Thursday night that safety Mike Williams is questionable for Saturday's Big Ten opener against Indiana.

Williams suffered a sprained left ankle in last week's win over Eastern Michigan and has been limited in practice this week.

"Mike Williams is a concern with his ankle," Rodriguez said. "That's probably going to be a game-time decision."

Rodriguez said Perry Dorrestein probably will start at right tackle as part of an overall reshuffling of the offensive line. Regular right guard David Moosman will start at center in place of the injured David Molk (broken foot), and Mark Huyge, who started the first three games at tackle, will slide inside to guard.

John Ferrara started at guard last week in place of Moosman, who was out with a shoulder injury.

Running back Brandon Minor remains a game-time decision, Rodriguez said, because of a nagging high-ankle sprain.

"We're trying to rest him during the week so he can be ready to go on Saturday, but really until gameday warm-ups will we really, truly know how much he can go," Rodriguez said.

Minor is not listed on Michigan's official injury report, and Williams is listed as doubtful.